Wednesday, Sept. 14, 2005
Thursday, Sept. 15, 2005
| Time |
Program and Speaker |
Title of presentation |
| from 8:00 |
Registration |
| 9:00 |
Opening of
meeting |
| 9:05 – 12:40 |
Session
I: Protein-Protein Interactions (Chair: W. Kühlbrandt) |
| 9:05 – 9:40 |
M. Wilmanns (Hamburg) |
Protein translocation into peroxisomes |
| 9:40 – 10:00 |
E. Sundberg (Watertown) |
Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction |
| 10:00 – 10:35 |
J. Hurley (NIH Bethesda) |
The ESCRT system: structure and mechanism of a membrane-associated network of trafficking proteins |
| 10:35 – 10:55 |
M. G. Bertero (München) |
The membrane-bound respiratory complex NarGHI from Escherichia coli |
| 10:55 – 11:25 |
coffee break |
| 11:25 – 11:45 |
E. De Genst (Brüssel) |
Molecular recognition and maturation of camelid heavy chain antibodies |
| 11:45 – 12:05 |
S. Grzesiek (Basel) |
NMR as a quantitative tool to study structure, dynamics and function of interacting biomacromolecules |
| 12:05 – 12:25 |
A. Meinhart (Heidelberg) |
Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors |
| 12:40 –
14:30 |
Lunch |
| 14:30 –
17:30 |
Session
II: Protein-Nucleic Acid Interactions (Chair: P.
Cramer) |
| 14:30 – 15:05 |
A. Pingoud
(Gießen) |
Engineering of meganucleases |
| 15:05 – 15:25 |
K. Armache (München) |
Macromolecular machines for gene transcription |
| 15:25 – 15:45 |
A. Deaconescu (New York) |
Structural basis for bacterial transcription-coupled DNA repair |
| 15:45 – 16:15 |
coffee break |
| 16:15 – 16:50 |
T. Steitz (Yale) |
Motion in macromolecular machines |
| 16:50 – 17:10 |
L.-O. Essen (Marburg) |
Structural aspects of blue light receptors involved in DNA repair and signaling |
| 17:10 – 17:30 |
E. Lorentzen (Heidelberg) |
Structural basis for the 3-end recognition of single-stranded RNAs by the archaeal exosome core |
| 17:45 – 18:15 |
Meeting of the GBM study group "Structural Biology" |
| 18:00 –
22:00 |
Poster Session
(with warm and cold buffet) |
Friday, Sept. 16, 2005
| Time |
Program and Speaker |
Title of presentation |
| 9:00 –
12:35 |
Session
III: Prediction and Design of Molecular Interactions (Chair: Y. Muller) |
| 9:00 – 9:35 |
A. Plückthun
(Zürich) |
Designed repeat proteins |
| 9:35 – 9:55 |
R. van Montfort (Cambridge) |
The molecular pharmacology of tubulin dynamics |
| 9:55 – 10:30 |
T. Kortemme (San Francisco) |
Prediction and design of specificity in molecular recognition |
| 10:30 – 10:50 |
M.-H. Le Du (Gif-sur-Yvette) |
Structure-function studies of tumour markers: evolution of diagnosis markers into therapeutic targets |
| 10:50 – 11:20 |
coffee break |
| 11:20 – 11:55 |
R. Russell (Heidelberg) |
Identifying structural details for protein-protein interactions |
| 11:55 – 12:15 |
T. Wollert (Braunschweig) |
Structure-based re-engeneering of internalin - the intestinal invasin of Listeria monocytogenes |
| 12:15 – 12:35 |
D. Röser (Göttingen) |
Molecular basis for multiple sulfatase deficiency and catalytic mechanism for formylglycine generation of the human formylglycine generating enzyme |
| 12:35 –
14:30 |
Lunch |
| 14:30 –
18:00 |
Session
IV: Dynamcis and Transient Interactions (Chair: M. Sattler) |
| 14:30 – 15:05 |
J. Ellis (Warwick) |
Macromolecular crowding and protein aggregation |
| 15:05 – 15:25 |
A. Schmidt (Hamburg) |
Exacting dynamic properties from crystal protein structures |
| 15:25 – 15:45 |
F. Allain (Zürich) |
Structural insight into splicing regulation with the solution structure of PTB and FOX-1 in complex with RNA |
| 15:45 – 16:15 |
coffee break |
| 16:15 – 16:50 |
H. Schwalbe (Frankfurt) |
NMR of RNA and of Kinases |
| 16:50 – 17:10 |
M. Görlach (Jena) |
Structure-function relationship in RNA tetraloops: an old chap in new garb |
| 17:10 – 17:30 |
H. Bartunik (Hamburg) |
Transient protein-ligand interactions during enzyme catalysis by EPSP synthase from M. tuberculosis |
| from 19:00 |
Conference
Dinner (in Griesbräu brewery) |
Saturday, Sept. 17, 2005
| Time |
Program and Speaker |
Title of presentation |
| 9:00 –
12:55 |
Session
V: Large Macromolecular Assemblies (Chair: M.
Grütter) |
| 9:00 – 9:35 |
H. Stark (Göttingen)
|
3D structures of snRNPs and spliceosomes by electron cryomicroscopy |
| 9:35 – 9:55 |
K. Model (Cambridge) |
Structural principles of cooperative protein translocators in outer and inner membranes of mitochondria revealed by electron microscopy |
| 9:55 – 10:30 |
N. Ban (Zürich) |
Structural aspects of co-translational protein folding and translocation |
| 10:30 – 10:50 |
E. Pyetan (Rehovot) |
Revealing the first steps in chaperone activity: Structure and dynamics of trigger factor in complex with eubacterial ribosome |
| 10:50 – 11:20 |
coffee break |
| 11:20 – 11:40 |
B. Rockel (Martinsried) |
Molecular architecture and assembly mechanism of tripeptidyl peptidase II |
| 11:40 – 12:00 |
M. Wahl (Göttingen |
Stalking the stalk |
| 12:00 – 12:20 |
I. Berger (Zürich) |
MultiBac: New Baculovirus expression tools for multiprotein applications |
| 12:20 – 12:55 |
M. Rossmann (Purdue) |
How tailed bacteriophages package and later eject their dsDNA genomes |
| 12:55 – 13:00 |
Concluding remarks |
| 13:00 |
End of meeting |
| from 14:30 |
Sightseeing
tour (Castle Neuschwanstein) |
