| Time |
Program and Speaker |
Title of presentation |
| from 8:00 |
Registration |
| 9:00 – 12:15 |
Session I: Transcription / Chair: M. Weiss |
| 9:00 – 9:45 |
P. Cramer (Munich) |
Global mechanisms of gene transcription |
| 9:45 – 10:05 |
M. Wilmanns (Hamburg) |
Structure-based design of a MafB transcription factor variant with altered coiled coil assembly and promoter preference properties in leukocytes |
| 10:05 – 10:35 |
N. Abrescia (Bilbao) |
Closer to eukarya: the structure of the complete archaeal RNA polymerase |
| 10:35 – 11:00 |
Coffee break |
| 11:00 – 11:20 |
P. Wollmann (Munich) |
Structure of the Mot1-TBP complex: insight into a Swi2/Snf2 enzyme-substrate interaction and remodeling mechanism |
| 11:20 – 11:40 |
K. Tripsianes (Munich) |
Structural basis for dimethyl-arginine recognition by Tudor domains |
| 11:40 – 12:10 |
F. Werner (London) |
The structure and mechanisms of RNAP subunits Rpo4/7 and the Spt4/5 complex during transcription elongation - the ′elongation-first hypothesis′ |
| 12:15 – 14:00 |
Lunch |
| 14:00 – 17:15 |
Session II : RNA processing / Chair: C. Kisker |
| 14:00 – 14:45 |
R. Lührmann (Göttingen) |
Structural dynamics and function of the spliceosome |
| 14:45 – 15:05 |
K. Lakomek (Göttingen) |
Crystal structure analysis of a 4-thiouridine synthetase - RNA complex reveals a molecular ruler for recognition of U8 of tRNAPhe in a non-canonical conformation |
| 15:05 – 15:35 |
A. Pyle (New Haven) |
Group II intron structural features and their implications for pre-mRNA splicing and the folding of multi-domain RNA molecules |
| 15:35 – 16:00 |
Coffee break |
| 16:00 – 16:20 |
B. Loll (Berlin) |
Is yeast Clp1 a "locked" mononucleoside kinase involved in 3′-end processing of mRNA? |
| 16:20 – 16:40 |
C. Mackereth (Pessac) |
Co-operative folding of the Rna14 monkeytail and Rna15 hinge domains in the yeast CF IA complex |
| 16:40 – 17:10 |
K. Nagai (Cambridge) |
The architecture of the spliceosomal U1 snRNP |
| 17:15 – 18:45 |
Poster Session part I / A-K |
| 19:00 |
Informal Conference Dinner in Foyer (buffet) |
| 20:00 |
Meeting of the GBM Study Group "Structural Biology" |
| Time |
Program and Speaker |
Title of presentation |
| 8:30 – 11:30 |
Session III : Regulatory RNA / Chair: M. Sattler |
| 8:30 – 9:15 |
J. Doudna (Berkeley) |
Regulatory RNA biogenesis for viral defense in bacteria |
| 9:15 – 9:35 |
O. Duss (Zürich) |
Solution structure of the 55 kDa trimolecular complex between the ncRNA RsmZ and two global regulatory protein RsmE dimers obtained using a new segmental isotope labeling approach of RNA |
| 9:35 – 10:05 |
D. Patel (New York) |
Structural Biology of Riboswitches, Nucleo-cytoplasmic Transport and hDicer-mediated RNA Cleavage |
| 10:05 – 10:30 |
Coffee break |
| 10:30 – 10:50 |
O. Weichenrieder (Tübingen) |
Structures of trimeric L1ORF1 protein
and its flexibility in the context of human LINE-1 retrotransposition |
| 10:50 – 11:20 |
J. Feigon (Los Angeles) |
Structure and Dynamics of Telomerase and Riboswitch RNAs |
| 11:20 – 13:00 |
Poster Session part II / L-Z |
| 13:00 – 14:00 |
Lunch |
| 14:00 – 16:00 |
Session IV: RNA turnover and decay / Chair: E. Conti |
| 14:00 – 14:45 |
C. Lima (New York) |
Structure and Function of Eukaryotic RNA Exosomes |
| 14:45 – 15:05 |
A. Murachelli (Munich) |
Structural and biochemical studies of the ASAP complex |
| 15:05 – 15:25 |
J. Henri (Orsay) |
Dom34-Hbs1 a complex involved in No-Go Decay and Non-functional rRNA Decay |
| 15:25 – 15:55 |
J. Gross (San Francisco) |
Dynamics and the control of mRNA decapping by Dcp2 |
| 16:00 – 19:30 |
Sightseeing (Wieskirche - UNESCO World Heritage Rococo church) |
| 20:00 |
Official Conference Dinner (Brewery - Bavarian Night + Poster Prizes) |
| Time |
Program and Speaker |
Title of presentation |
| 9:00 – 11.45 |
Session V: Translation / Chair: H. Stark |
| 9:00 – 9:45 |
V. Ramakrishnan (Cambridge) |
How the ribosome ensures the fidelity of decoding mRNA |
| 9:45 – 10:05 |
C. Schaffitzel (Grenoble) |
Structure of the E. coli co-translational targeting complex in the early checkpoint state |
| 10:05 – 10:25 |
S. Ataide (Zürich) |
The crystal structure of the signal recognition particle in complex with its receptor |
| 10:25 – 10:50 |
Coffee break |
| 10:50 – 11:10 |
N. Fischer (Göttingen) |
Ribosome dynamics and tRNA movement as visualized by time-resolved electron cryomicroscopy |
| 11:10 – 11:30 |
R. Knudsen (Aarhus) |
Structural insight into how a virus exploits its host |
| 11:30 – 12:00 |
R. Beckmann (Munich) |
Cryo-EM of nascent polpypeptide chains |
| 12:00 |
Final discussion and outlook |
moderation: P. Cramer, E. Conti, D. Heinz |
| 12:55 |
Closing remarks and farewell |
D.Heinz |
| 13:00 |
End of meeting |
