Program and Schedule 2024
September 18, 2024 (Wednesday)
16:00 |
Registration open |
17:00 |
Informal get-together, dinner buffet |
19:00 |
Conference Opening - Welcome Note |
19:15 |
The Murnau Lecture 2024 |
20:15 |
Beer and snacks |
September 19, 2024 (Thursday)
8:30 |
Registration open |
Session 1 |
Dynamic Processes Chair: Janosch Hennig |
09:00 |
Katja Petzold - What do microRNAs and ribosomes have in common? - GBM Lecture |
09:40 |
Jessica Schmuck - NMR spectroscopy of self-hydrolysing NMR |
09:55 |
Philipp Neudecker - Transverse Relaxation Optimized Spectroscopy in the Presence of Chemical Exchange at 1.2 GHz |
10:10 | Till Rudack -
Beyond static structures: Integrating cryo-EM, NMR and MD simulations to create complete struc tural dynamic models of macromolecular machines |
10:25 |
Coffee break |
10:55 |
Claus Seidel - Integrative dynamic structural biology with multi-modal fluorescence spectroscopy: Making structural and associated kinetic information accessible - GBM Lecture |
11:35 |
Benedikt Kuhn - Structure and function of the multi-functional solute carrier SLC26A11 |
11:50 |
Anastasiia Chaban - Real-time tracking of early ribosomal RNA transcription and processing |
12:05 |
Georgios Skiniotis - Time-resolved cryoEM of G protein activation by a GPCR |
12:20 |
Lunch with poster session and exhibition (even numbered posters) |
Session 2 |
In situ Structural Biology Chair: Cristina Paulino |
14:00 |
Julia Mahamid - Enabling discovery by in-cell structural biology - GBM Lecture |
14:40 |
Mareike Jordan - LEM2-ESCRT filaments form a diffusion barrier during nuclear envelope reformation |
14:55 |
Stefan Raunser - Unlocking the secrets of heart muscle structure - GBM Lecture |
15:35 |
Coffee break |
Session 3 |
Current and future of X-ray Crystallography Chair: Oliver Einsle |
16:00 |
Thomas Schneider - MX -Quo vadis? - GBM Lecture |
16:40 |
Kim Bartels - SPITROBOT-2: 4D Crystallography at Double the Speed, Half the Effort |
16:55 |
Janina Gerber - Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease |
17:10 | Sophie Korn -
A core network in the SARS-CoV-2 Nucleocapsid NTD orchestrates RNA recognition |
17:25 |
Business meeting for GBM members (ca. 20 min), |
18:30 |
Dinner buffet with poster session and exhibition |
September 20, 2024 (Friday)
Session 4 |
Integrative Structural Biology & cryo-EM | Chair: Irmgard Sinning |
09:00 |
Elena Seiradake - Structural switches direct neuronal migration in the developing cortex - GBM Lecture |
09:40 |
Andreas Schlundt - An integrated approach to deconvolute a full-length mRNA 3’UTR and its interaction with a multi-domain RNA-binding protein |
09:55 |
Yasmine Damayanti - A disease-causing mutation in the disordered TRPV4 N-terminus modulates lipid-dependent chan nel activity |
10:10 | Simone Heber - Reconstitution of oskar RNA transport elucidates the mechanisms behind RNP remodeling and motor-switching |
10:25 |
Coffee break |
10:55 |
Sebastian Hiller - The Functional Cycle of Hsp70 Chaperone - GBM Lecture |
11:35 |
Patricia Rothe - Mechanism for the initiation of spliceosome disassembly |
11:50 |
Vladimir Arinkin - Structures of the Sleeping Beauty transpososome during excision and integration |
12:05 | Henriette Ebel -
Deciphering molecular details of the herpes simplex virus 1 fusion machinery |
12:20 |
Lunch with poster session and exhibition (all posters) |
13:30 |
Free afternoon Optional: Guided sightseeing tour |
Session 5 |
AI-supported Structural Biology & Method Development | Chair: Till Rudack |
16:30 |
Roberto Covino - From Pixels to Bayesian Posteriors: Fast Molecular Conformation Estimation from Cryo-EM with simulation-based inference - GBM Lecture |
17:10 |
Sergio Cruz - Towards modeling cellular environments: Bridging cryo-electron tomography and simulations with high confidence 3D template matching |
17:25 |
Thermofisher - Deniz Ugular - Accelerating Cryo-EM Structure-Based Drug Design with Glacios 2 and Smart EPU |
17:37 | CryoCloud - Robert Engelmeier -
Towards automating cryo-EM data analysis: overcoming challenges of particle localiza tion & preferred orientation |
17:50 |
Coffee break |
18:20 |
Burkhard Rost - Artificial Intelligence deciphers the code of life written in proteins? - GBM Lecture |
19:00 |
Sören von Bülow - Prediction of phase separation propensities of disordered proteins from sequence |
19:15 |
Miriam Weber - Simplified High-Pressure Freezing Workflow in Autogrids |
19:30 |
Christian Hanke - Generating FRET-based integrative structural models and depositing them together with kinetic in formation |
19:45 | Walk to Brauhaus Griesbräu |
20:15 |
Conference dinner at Brauhaus Griesbräu, Murnau |
September 21, 2024 (Saturday)
Session 6 |
Complementary methods | Chair: Andreas Schlundt |
09:00 |
Jörg Standfuss - Photopharmacology the movie - Drug release from tubulin at atomic resolution and fourteen orders of magnitude in time - GBM Lecture |
09:40 |
Franziska Elsässer - A structural proteomics approach captures protein structure dynamics and biomolecular condensation in living cells |
09:55 |
Olivier Duss - Tracking assembly, function and coupling of single active protein-RNA complexes in real-time - GBM Lecture |
10:35 | Agata Misiaszek -
Towards long-term imaging of single mRNAs and associated with them translation factors |
10:50 |
Coffee break |
Session 7 | More Amazing Structural Biology | Chair: Milton Stubbs |
11:20 |
Bettina Böttcher - Lymphostatin: Structure of a nontoxic Toxin |
11:35 |
Esther Hudina - Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies |
11:50 | Komal Soni -
Structure of an aberrant spliceosome intermediate on its way to disassembly |
12:05 | George Broutzakis -
High-resolution structures of the UapA elevator-type purine transporter rationalize the importance of the cytosolic N-terminus in trafficking and transport activity |
12:20 | Mariya Lazarova -
A phylogenetic determinant of conformational plasticity affects antibiotic transport by RND multi drug efflux pumps |
12:35 |
Closing remarks, poster award ceremony and end of meeting |